IDX-375
| Code | Size | Price |
|---|
| TAR-T27587-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
IDX-375, a HCV NS5B polymerase inhibitor, is used potentially for the treatment of HCV infection.
CAS:
1256735-81-5
Formula:
C29H50N5O7PS
Molecular Weight:
643.78
Purity:
0.98
SMILES:
C[N+](C)(C)CCO.CC(C)(C)CCN1C(C([O-])=C(C1=O)C1=NP(=O)(CCO)c2cc(NS(C)(=O)=O)ccc2N1)C(C)(C)C
References
1. Valese AC, Vitali L, Fett R, Micke GA, de Oliveira MA, Oliveira Costa AC. A Rapid Method for Analysis of Phenylalanine in Cereal Products by MEKC-UV Using LC/MS/MS as a Comparative Method. J AOAC Int. 2015 Nov-Dec;98(6):1632-9. doi: 10.5740/jaoacint.15-052. PubMed PMID: 26651576.
2. Vitali L, Della Betta F, Costa AC, Vaz FA, Oliveira MA, Vistuba JP, F?vere VT, Micke GA. New multilayer coating using quaternary ammonium chitosan and ?-carrageenan in capillary electrophoresis: application in fast analysis of betaine and methionine. Talanta. 2014 Jun;123:45-53. doi: 10.1016/j.talanta.2014.01.047. PubMed PMID: 24725863.
3. de Bruijne J, van de Wetering de Rooij J, van Vliet AA, Zhou XJ, Temam MF, Molles J, Chen J, Pietropaolo K, Sullivan-B?lyai JZ, Mayers D, Reesink HW. First-in-human study of the pharmacokinetics and antiviral activity of IDX375, a novel nonnucleoside hepatitis C virus polymerase inhibitor. Antimicrob Agents Chemother. 2012 Aug;56(8):4525-8. doi: 10.1128/AAC.00451-12. PubMed PMID: 22664976; PubMed Central PMCID: PMC3421546.