LY 97241
Code | Size | Price |
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TAR-T27927-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27927-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T27927-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
LY 97241 is an inhibitor of hEAG1 and hERG1 potassium channel.
CAS:
72456-63-4
Formula:
C19H32N2O2
Molecular Weight:
320.477
Purity:
0.98
SMILES:
CCCCCCCN(CC)CCCCc1ccc(cc1)[N+]([O-])=O
References
1. Gessner G, Zacharias M, Bechstedt S, Sch?nherr R, Heinemann SH. Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents. Mol Pharmacol. 2004 May;65(5):1120-9. PubMed PMID: 15102940.
2. Gessner G, Heinemann SH. Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241. Br J Pharmacol. 2003 Jan;138(1):161-71. PubMed PMID: 12522086; PubMed Central PMCID: PMC1573651.
3. Finlayson K, Turnbull L, January CT, Sharkey J, Kelly JS. [3H]dofetilide binding to HERG transfected membranes: a potential high throughput preclinical screen. Eur J Pharmacol. 2001 Oct 26;430(1):147-8. PubMed PMID: 11698075.
4. Steidl JV, Yool AJ. Distinct mechanisms of block of Kv1.5 channels by tertiary and quaternary amine clofilium compounds. Biophys J. 2001 Nov;81(5):2606-13. PubMed PMID: 11606274; PubMed Central PMCID: PMC1301728.