Milfasartan
Code | Size | Price |
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TAR-T28039-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28039-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28039-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Milfasartan is a potent, selective antagonist of AT1 receptor with oral activity. It markedly lowers the blood-pressure in conscious renal and spontaneously hypertensive rats.
CAS:
148564-47-0
Formula:
C30H30N6O3S
Molecular Weight:
554.67
Purity:
0.98
SMILES:
CCCCc1nc(C)n(Cc2sccc2C(=O)OC)c(=O)c1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
References
1. Soave R, Barzaghi M, Destro R. Progress in the understanding of drug-receptor interactions, part 2: experimental and theoretical electrostatic moments and interaction energies of an angiotensin II receptor antagonist (C30H30N6(O)3S). Chemistry. 2007;13(24):6942-56. PubMed PMID: 17539033.
2. Destro R, Soave R, Barzaghi M, Lo Presti L. Progress in the understanding of drug-receptor interactions, Part 1: experimental charge-density study of an angiotensin II receptor antagonist (C30H30N6O3S) at T = 17 K. Chemistry. 2005 Aug 5;11(16):4621-34. PubMed PMID: 15915518.
3. No?l B, Del Re G, Capone P, Brunner HR, Nussberger J. Clinical and hormonal effects of the new angiotensin II receptor antagonist LRB081. J Cardiovasc Pharmacol. 1996 Aug;28(2):252-8. PubMed PMID: 8856481.
4. Polidori C, Ciccocioppo R, Pompei P, Cirillo R, Massi M. Functional evidence for the ability of angiotensin AT1 receptor antagonists to cross the blood-brain barrier in rats. Eur J Pharmacol. 1996 Jul 4;307(3):259-67. PubMed PMID: 8836613.