Telenzepine
Code | Size | Price |
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TAR-T28941-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28941-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28941-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Telenzepine is a potent and selective M1 antimuscarinic.
CAS:
80880-90-6
Formula:
C19H23N4O2S
Molecular Weight:
371.48
Purity:
0.98
SMILES:
CN1CCN(CC(=O)C2=NC3=C(CCC=C3)[N](=O)c3csc(C)c23)CC1
References
1. Pelosi A, Menardy F, Popa D, Girault JA, Herv? D. Heterozygous Gnal mice are a novel animal model to study dystonia pathophysiology. J Neurosci. 2017 May 25. pii: 1529-16. doi: 10.1523/JNEUROSCI.1529-16.2017. [Epub ahead of print] PubMed PMID: 28546310.
2. Joseph L, Thomsen M. Effects of muscarinic receptor antagonists on cocaine discrimination in wild-type mice and in muscarinic receptor M(1), M(2), and M(4) receptor knockout mice. Behav Brain Res. 2017 Apr 22;329:75-83. doi: 10.1016/j.bbr.2017.04.023. [Epub ahead of print] PubMed PMID: 28442355.
3. Ztaou S, Maurice N, Camon J, Guiraudie-Capraz G, Kerkerian-Le Goff L, Beurrier C, Liberge M, Amalric M. Involvement of Striatal Cholinergic Interneurons and M1 and M4 Muscarinic Receptors in Motor Symptoms of Parkinson's Disease. J Neurosci. 2016 Aug 31;36(35):9161-72. doi: 10.1523/JNEUROSCI.0873-16.2016. PubMed PMID: 27581457.
4. Pediani JD, Ward RJ, Godin AG, Marsango S, Milligan G. Dynamic Regulation of Quaternary Organization of the M1 Muscarinic Receptor by Subtype-selective Antagonist Drugs. J Biol Chem. 2016 Jun 17;291(25):13132-46. doi: 10.1074/jbc.M115.712562. Epub 2016 Apr 14. PubMed PMID: 27080256; PubMed Central PMCID: PMC4933229.