Topixantrone
Code | Size | Price |
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TAR-T28994-5mg | 5mg | £790.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28994-50mg | 50mg | £1,821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T28994-100mg | 100mg | £2,319.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Topixantrone, a DNA topoisomerase inhibitor, is used potentially for the treatment of gastric cancer and prostate cancer.
CAS:
156090-18-5
Formula:
C21H26N6O2
Molecular Weight:
394.479
Purity:
0.98
SMILES:
CN(C)CCNc1ccc2n(CCNCCO)nc3-c4cnccc4C(=O)c1c23
References
1. Marini A, Berbenni V, Bruni G, Cofrancesco P, Margheritis C, Orlandi A, Villa M. Hydration, stability, and phase transformations of a new antitumor drug. J Pharm Sci. 2004 Sep;93(9):2222-31. PubMed PMID: 15295783.
2. Mross K, Scheulen ME, Licht T, Unger C, Richly H, Stern AC, Kutz K, Camboni MG, Barbieri P, Verdi E, Vincenzi B, Bernareggi A. Phase I clinical and pharmacokinetic study of BBR 3576, a novel aza-anthrapyrazole, administered i.v. every 4 weeks in patients with advanced solid tumors: a phase I study group trial of the Central European Society of Anticancer-Drug Research (CESAR). Anticancer Drugs. 2004 Jan;15(1):15-22. PubMed PMID: 15090738.