Tanshinone IIA
| Code | Size | Price |
|---|
| TAR-T2906-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T2906-20mg | 20mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tanshinone IIA(Tanshinone B) is the diterpene quinone in Danshen, which is utilized in the treatment of cardiovascular and inflammatory.
CAS:
568-72-9
Formula:
C19H18O3
Molecular Weight:
294.35
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.9954
SMILES:
Cc1coc-2c1C(=O)C(=O)c1c3CCCC(C)(C)c3ccc-21
Target:
VEGFR
References
1. Fu J, et al. Eur J Pharmacol, 2007, 568(1-3), 213-221.
2. Wang X, et al. Int J Cancer, 2005, 116(5), 799-807.
3. Sun S, et al. Brain Res Bull, 2012, 88(6), 581-588.
4. Ruolin Yang, et al. Med. Chem. Commun., 2014, 5: 1528-1532.
6. Zhang Z, et al. Tanshinone IIA inhibits apoptosis in the myocardium by inducing microRNA-152-3p expression and thereby downregulating PTEN. Am J Transl Res. 2016 Jul 15;8(7):3124-32.
7. Su CC, et al. Tanshinone IIA decreases the protein expression of EGFR, and IGFR blocking the PI3K/Akt/mTOR pathway in gastric carcinoma AGS cells both in vitro and in vivo. Oncol Rep. 2016 Aug;36(2):1173-9.