Acetylaranotin
Code | Size | Price |
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TAR-T29597-5mg | 5mg | £3,018.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T29597-50mg | 50mg | £5,998.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T29597-100mg | 100mg | £8,584.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Acetylaranotin belongs to one structural subgroup of ETPs characterized by the presence of a seven-membered 4,5-dihydrooxepine ring.
CAS:
20485-01-2
Formula:
C22H20N2O8S2
Molecular Weight:
504.53
Purity:
0.98
SMILES:
CC(=O)O[C@H]1C=COC=C2C[C@@]34SS[C@]5(CC6=COC=C[C@H](OC(C)=O)[C@@H]6N5C3=O)C(=O)N4[C@@H]12
References
1. Guo CJ, Yeh HH, Chiang YM, Sanchez JF, Chang SL, Bruno KS, Wang CC. Biosynthetic pathway for the epipolythiodioxopiperazine acetylaranotin in Aspergillus terreus revealed by genome-based deletion analysis. J Am Chem Soc. 2013 May 15;135(19):7205-13. doi: 10.1021/ja3123653. Epub 2013 May 1. PubMed PMID: 23586797; PubMed Central PMCID: PMC3695726.
2. Fujiwara H, Kurogi T, Okaya S, Okano K, Tokuyama H. Total synthesis of (-)-acetylaranotin. Angew Chem Int Ed Engl. 2012 Dec 21;51(52):13062-5. doi: 10.1002/anie.201207307. Epub 2012 Nov 19. PubMed PMID: 23161829.
3. Belov DS, Ratmanova NK, Andreev IA, Kurkin AV. Synthesis of bicyclic proline derivatives by the aza-Cope-Mannich reaction: formal synthesis of (?)-acetylaranotin. Chemistry. 2015 Mar 2;21(10):4141-7. doi: 10.1002/chem.201405811. Epub 2015 Jan 28. PubMed PMID: 25631763.
4. Codelli JA, Puchlopek AL, Reisman SE. Enantioselective total synthesis of (-)-acetylaranotin, a dihydrooxepine epidithiodiketopiperazine. J Am Chem Soc. 2012 Feb 1;134(4):1930-3. doi: 10.1021/ja209354e. Epub 2011 Oct 28. PubMed PMID: 22023250; PubMed Central PMCID: PMC3271125.