Ampelopsin C
| Code | Size | Price |
|---|
| TAR-T30035-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ampelopsin C protects endothelial cells from hyperglycemia-induced oxidative damage by inducing autophagy via the AMPK signaling pathway.
CAS:
130518-20-6
Formula:
C42H32O9
Molecular Weight:
680.709
Purity:
0.98
SMILES:
[H][C@]12[C@@H]([C@H](c3c1c1c(O[C@@H](c4ccc(O)cc4)[C@]1([H])c1cc(O)cc(O)c1[C@H]2c1ccc(O)cc1)cc3O)c1ccc(O)cc1)c1cc(O)cc(O)c1
References
1. Chen XM, Xie XB, Zhao Q, Wang F, Bai Y, Yin JQ, Jiang H, Xie XL, Jia Q, Huang G. Ampelopsin induces apoptosis by regulating multiple c-Myc/S-phase kinase-associated protein 2/F-box and WD repeat-containing protein 7/histone deacetylase 2 pathways in human lung adenocarcinoma cells. Mol Med Rep. 2015 Jan;11(1):105-12. doi: 10.3892/mmr.2014.2733. Epub 2014 Oct 21. PubMed PMID: 25333250; PubMed Central PMCID: PMC4237074.
2. Liang X, Zhang T, Shi L, Kang C, Wan J, Zhou Y, Zhu J, Mi M. Ampelopsin protects endothelial cells from hyperglycemia-induced oxidative damage by inducing autophagy via the AMPK signaling pathway. Biofactors. 2015 Nov-Dec;41(6):463-75. doi: 10.1002/biof.1248. Epub 2015 Dec 8. PubMed PMID: 26644014.
3. Qi S, Kou X, Lv J, Qi Z, Yan L. Ampelopsin induces apoptosis in HepG2 human hepatoma cell line through extrinsic and intrinsic pathways: Involvement of P38 and ERK. Environ Toxicol Pharmacol. 2015 Nov;40(3):847-54. doi: 10.1016/j.etap.2015.09.015. Epub 2015 Sep 30. PubMed PMID: 26476886.
4. Kou X, Shen K, An Y, Qi S, Dai WX, Yin Z. Ampelopsin inhibits H?O?-induced apoptosis by ERK and Akt signaling pathways and up-regulation of heme oxygenase-1. Phytother Res. 2012 Jul;26(7):988-94. doi: 10.1002/ptr.3671. Epub 2011 Dec 6. PubMed PMID: 22144097.