Amphimedine
| Code | Size | Price |
|---|
| TAR-T30039-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Amphimedine is a Pyridoacridine Marine Alkaloid.
CAS:
86047-14-5
Formula:
C19H11N3O2
Molecular Weight:
313.316
Purity:
0.98
SMILES:
Cn1cc2C(=O)c3nccc4c5ccccc5nc(-c2cc1=O)c34
References
1. Khalil IM, Barker D, Copp BR. Bioinspired Syntheses of the Pyridoacridine Marine Alkaloids Demethyldeoxyamphimedine, Deoxyamphimedine, and Amphimedine. J Org Chem. 2016 Jan 4;81(1):282-9. doi: 10.1021/acs.joc.5b02312. Epub 2015 Dec 17. PubMed PMID: 26642369.
2. Sharma V, Sharma PC, Kumar V. A mini review on pyridoacridines: Prospective lead compounds in medicinal chemistry. J Adv Res. 2015 Jan;6(1):63-71. doi: 10.1016/j.jare.2014.11.002. Epub 2014 Nov 15. Review. PubMed PMID: 25685544; PubMed Central PMCID: PMC4293674.
3. Brahic C, Darro F, Belloir M, Bastide J, Kiss R, Delfourne E. Synthesis and cytotoxic evaluation of analogues of the marine pyridoacridine amphimedine. Bioorg Med Chem. 2002 Sep;10(9):2845-53. PubMed PMID: 12110304.
4. Melzer B, Plodek A, Bracher F. Total synthesis of the marine pyridoacridine alkaloid demethyldeoxyamphimedine. J Org Chem. 2014 Aug 1;79(15):7239-42. doi: 10.1021/jo501312d. Epub 2014 Jul 18. PubMed PMID: 25081029.