Bis-T-23
Code | Size | Price |
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TAR-T30479-1mg | 1mg | £352.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30479-5mg | 5mg | £736.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30479-10mg | 10mg | £978.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30479-25mg | 25mg | £1,348.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30479-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30479-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T30479-500mg | 500mg | £4,006.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Bis-T-23 is a promoter of actin-dependent dynamin oligomerization.
CAS:
171674-76-3
Formula:
C23H20N4O8
Molecular Weight:
480.433
Pathway:
Microbiology/Virology|Proteases/Proteasome
Purity:
0.98
SMILES:
Oc1cc(C=C(/C#N)C(=O)NCCCNC(=O)C(=Cc2cc(O)c(O)c(O)c2)C#N)cc(O)c1O
Target:
HIV Protease
References
1. Sever S, Schiffer M. Actin dynamics at focal adhesions: a common endpoint and putative therapeutic target for proteinuric kidney diseases. Kidney Int. 2018 Jun;93(6):1298-1307. doi: 10.1016/j.kint.2017.12.028. Epub 2018 Apr 17. Review. PubMed PMID: 29678354; PubMed Central PMCID: PMC5967993.
2. Ono S, Kume S, Yasuda-Yamahara M, Yamahara K, Takeda N, Chin-Kanasaki M, Araki H, Sekine O, Yokoi H, Mukoyama M, Uzu T, Araki SI, Maegawa H. O-linked ?-N-acetylglucosamine modification of proteins is essential for foot process maturation and survival in podocytes. Nephrol Dial Transplant. 2017 Sep 1;32(9):1477-1487. doi: 10.1093/ndt/gfw463. PubMed PMID: 28339907.
3. Gu C, Lee HW, Garborcauskas G, Reiser J, Gupta V, Sever S. Dynamin Autonomously Regulates Podocyte Focal Adhesion Maturation. J Am Soc Nephrol. 2017 Feb;28(2):446-451. doi: 10.1681/ASN.2016010008. Epub 2016 Jul 18. PubMed PMID: 27432739; PubMed Central PMCID: PMC5280009.
4. Del Nogal-Avila M, Donoro-Blazquez H, Saha MK, Marshall CB, Clement LC, Mac? CE, Chugh SS. Novel therapeutic approaches for chronic kidney disease due to glomerular disorders. Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F63-5. doi: 10.1152/ajprenal.00245.2016. Epub 2016 May 4. Review. PubMed PMID: 27147672; PubMed Central PMCID: PMC4967169.