CI 922
| Code | Size | Price |
|---|
| TAR-T30916-5mg | 5mg | £1,251.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T30916-50mg | 50mg | £2,464.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T30916-100mg | 100mg | £3,283.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
CI 922 is an anaphylaxis mediator release inhibitor. It inhibits the activation of human neutrophils.
CAS:
97958-08-2
Formula:
C26H30N10O6
Molecular Weight:
578.59
Purity:
0.98
SMILES:
N[C@@H](CCCNC(N)=N)C(O)=O.COc1c(oc2c3cc(OC)ccc3n(-c3ccccc3)c12)C(=O)Nc1nnn[nH]1
References
1. Werns SW, Eller BT, Shea MJ, Simpson PJ, Dysko RC, Abrams GD, Lucchesi BR. Protection of reperfused ischemic canine myocardium by CI-922, a new inhibitor of leukocyte activation. J Cardiovasc Pharmacol. 1988;12(5):608-14. PubMed PMID: 2468062.
2. Wright CD, Hoffman MD, Thueson DO, Conroy MC. Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-922: mechanism of inhibitory activity. Biochem Biophys Res Commun. 1987 Nov 13;148(3):1110-7. PubMed PMID: 2825675.
3. Wright CD, Hoffman MD, Thueson DO, Conroy MC. Inhibition of human neutrophil activation by the allergic mediator release inhibitor, CI-922: differential inhibition of responses to a variety of stimuli. J Leukoc Biol. 1987 Jul;42(1):30-5. PubMed PMID: 2439626.
4. Adolphson RL, Finkel MP, Robichaud LJ. CI-922--a novel, potent antiallergic compound--II. Activity in animal models of allergy. Int J Immunopharmacol. 1987;9(1):51-60. PubMed PMID: 2438239.