Desferrithiocin
| Code | Size | Price |
|---|
| TAR-T31387-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Desferrithiocin is a more active iron chelator than desferrioxamine.
CAS:
105635-69-6
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
1. Taher AT, Saliba AN, Kuo KH, Giardina PJ, Cohen AR, Neufeld EJ, Aydinok Y, Kwiatkowski JL, Jeglinski BI, Pietropaolo K, Berk G, Viprakasit V. Safety and pharmacokinetics of the oral iron chelator SP-420 in ?-thalassemia. Am J Hematol. 2017 Dec;92(12):1356-1361. doi: 10.1002/ajh.24914. Epub 2017 Oct 31. PubMed PMID: 28940308.
2. Kaviani S, Izadyar M, Housaindokht MR. A DFT study on the complex formation between desferrithiocin and metal ions (Mg(2+), Al(3+), Ca(2+), Mn(2+), Fe(3+), Co(2+), Ni(2+), Cu(2+), Zn(2+)). Comput Biol Chem. 2017 Apr;67:114-121. doi: 10.1016/j.compbiolchem.2016.12.012. Epub 2017 Jan 3. PubMed PMID: 28068516.
3. Bergeron RJ, Bharti N, McManis JS, Wiegand J. Metabolically programmed iron chelators. Bioorg Med Chem. 2015 Sep 1;23(17):5954-71. doi: 10.1016/j.bmc.2015.06.059. Epub 2015 Jun 29. PubMed PMID: 26231739; PubMed Central PMCID: PMC4608554.
4. Hider RC, Kong X, Abbate V, Harland R, Conlon K, Luker T. Deferitazole, a new orally active iron chelator. Dalton Trans. 2015 Mar 21;44(11):5197-204. doi: 10.1039/c5dt00063g. PubMed PMID: 25687725.