DIBA
| Code | Size | Price |
|---|
| TAR-T31424-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
DIBA is an ER zinc finger inhibitor that inhibits ligand-dependent and non-dependent cell growth in TAM resistant breast cancer in vitro and in vivo.
CAS:
171744-39-1
Formula:
C26H22N4O6S4
Molecular Weight:
614.72
Purity:
0.98
SMILES:
NS(=O)(=O)c1ccc(NC(=O)c2ccccc2SSc2ccccc2C(=O)Nc2ccc(cc2)S(N)(=O)=O)cc1
References
1. Wang LH, Yang XY, Zhang X, An P, Kim HJ, Huang J, Clarke R, Osborne CK, Inman JK, Appella E, Farrar WL. Disruption of estrogen receptor DNA-binding domain and related intramolecular communication restores tamoxifen sensitivity in resistant breast cancer. Cancer Cell. 2006 Dec;10(6):487-99. PubMed PMID: 17157789.