Ganoderiol A
| Code | Size | Price |
|---|
| TAR-T31910-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ganoderiol A is a tetracyclic triterpene extracted from Ganoderma amboinense.
CAS:
106518-61-0
Formula:
C30H50O4
Molecular Weight:
474.726
Purity:
0.98
SMILES:
[H][C@@]12CC=C3C(=CC[C@]4(C)[C@H](CC[C@@]34C)[C@H](C)CC[C@H](O)C(C)(O)CO)[C@@]1(C)CC[C@H](O)C2(C)C
References
1. Wu GS, Song YL, Yin ZQ, Guo JJ, Wang SP, Zhao WW, Chen XP, Zhang QW, Lu JJ, Wang YT. Ganoderiol A-enriched extract suppresses migration and adhesion of MDA-MB-231 cells by inhibiting FAK-SRC-paxillin cascade pathway. PLoS One. 2013 Oct 29;8(10):e76620. doi: 10.1371/journal.pone.0076620. eCollection 2013. PubMed PMID: 24204647; PubMed Central PMCID: PMC3812178.
2. Chang UM, Li CH, Lin LI, Huang CP, Kan LS, Lin SB. Ganoderiol F, a ganoderma triterpene, induces senescence in hepatoma HepG2 cells. Life Sci. 2006 Aug 15;79(12):1129-39. Epub 2006 Mar 28. PubMed PMID: 16635496.
3. Liu JQ, Wang CF, Li Y, Luo HR, Qiu MH. Isolation and bioactivity evaluation of terpenoids from the medicinal fungus Ganoderma sinense. Planta Med. 2012 Mar;78(4):368-76. doi: 10.1055/s-0031-1280441. Epub 2011 Dec 12. PubMed PMID: 22161763.
4. Zhang Q, Zuo F, Nakamura N, Ma CM, Hattori M. Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum. J Nat Med. 2009 Jul;63(3):304-10. doi: 10.1007/s11418-009-0337-5. Epub 2009 May 1. PubMed PMID: 19407927.