IPI-493
| Code | Size | Price |
|---|
| TAR-T32188-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
IPI-493 is a bioactive chemical.
CAS:
64202-81-9
Formula:
C28H39N3O8
Molecular Weight:
545.633
Purity:
0.98
SMILES:
CO[C@H]1C[C@H](C)CC2=C(N)C(=O)C=C(NC(=O)C(C)=CC=C[C@H](OC)[C@@H](OC(N)=O)C(C)=C[C@H](C)[C@H]1O)C2=O
References
1. Porter, James R.; Puri, Sonali. Ansamycin hydroquinone compositions for the treatment of hyperproliferative disorders. PCT Int. Appl. (2010), 101pp. CODEN: PIXXD2 WO 2010045442 A1 20100422 CAN 152:493438 AN 2010:499720
2. Porter, James R.; Ge, Jie; Lee, John; Normant, Emmanuel; West, Kip. Ansamycin inhibitors of Hsp90: nature's prototype for anti-chaperone therapy. Current Topics in Medicinal Chemistry (Sharjah, United Arab Emirates) (2009), 9(15), 1386-1418. CODEN: CTMCCL ISSN:1568-0266. CAN 152:421418 AN 2010:152784
3. Douglas, Mark; Lim, Alice R.; Porter, James R.; West, Kip; Pink, Melissa M.; Ge, Jie; Wylie, Andrew A.; Tibbits, Thomas T.; Biggs, Kurtis; Curtis, Michael; Palombella, Vito J.; Adams, Julian; Fritz, Christian C.; Normant, Emmanuel. The antiproliferative activity of the heat shock protein 90 inhibitor IPI-504 is not dependent on NAD(P)H:quinone oxidoreductase 1 activity in vivo. Molecular Cancer Therapeutics (2009), 8(12), 3369-3378. CODEN: MCTOCF ISSN:1535-7163. CAN 152:206394 AN 2009:1541742
4. Horton, William A.; Laederich, Melanie B. HSP90 inhibitors for the treatment for achondroplasia and other FGF receptor-mediated conditions. U.S. Pat. Appl. Publ. (2009), 62 pp. CODEN: USXXCO US 2009192133 A1 20090730 CAN 151:212530 AN 2009:919310