Leustroducsin B
Code | Size | Price |
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TAR-T32687-5mg | 5mg | £3,581.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T32687-50mg | 50mg | £7,123.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T32687-100mg | 100mg | £10,271.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.
CAS:
145142-82-1
Formula:
C34H56NO10P
Molecular Weight:
669.793
Purity:
0.98
SMILES:
CCC(C)CCCCC(=O)OC1CCCC(C1)C=CC=CC(O)CC(OP(O)(O)=O)C(O)(CCN)C=CC1OC(=O)C=CC1CC
References
1. Trost BM, Biannic B, Brindle CS, O'Keefe BM, Hunter TJ, Ngai MY. A Highly Convergent Total Synthesis of Leustroducsin B. J Am Chem Soc. 2015 Sep 16;137(36):11594-7. doi: 10.1021/jacs.5b07438. Epub 2015 Sep 1. PubMed PMID: 26313159; PubMed Central PMCID: PMC4621997.
2. Greszler SN, Malinowski JT, Johnson JS. Formal synthesis of leustroducsin B via Reformatsky/Claisen condensation of silyl glyoxylates. Org Lett. 2011 Jun 17;13(12):3206-9. doi: 10.1021/ol2011192. Epub 2011 May 17. PubMed PMID: 21591684; PubMed Central PMCID: PMC3115596.
3. Miyashita K, Tsunemi T, Hosokawa T, Ikejiri M, Imanishi T. Total synthesis of leustroducsin B. J Org Chem. 2008 Jul 18;73(14):5360-70. doi: 10.1021/jo8005599. Epub 2008 Jun 13. PubMed PMID: 18549287.
4. Koishi R, Yoshimura C, Kohama T, Serizawa N. Leustroducsin B activates nuclear factor-kappaB via the acidic sphingomyelinase pathway in human bone marrow-derived stromal cell line KM-102. J Interferon Cytokine Res. 2002 Mar;22(3):343-50. PubMed PMID: 12034042.