Lnd 796
Code | Size | Price |
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TAR-T32830-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Lnd 796 is an aminosteroid related to LND 623.
CAS:
118549-42-1
Formula:
C27H45NO7
Molecular Weight:
495.657
Purity:
0.98
SMILES:
[H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)[C@H](CC[C@]34N)C(=O)OC)[C@@]1(C)CC[C@@H](C2)O[C@@H]1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O
References
1. Maixent JM, F?nard S, Kawamoto RM. Tissue localization of active Na,K-ATPase isoenzymes by determination of their profile of inhibition with ouabain, digoxin, digitoxigenin and LND 796, a new aminosteroid cardiotonic. J Recept Res. 1991;11(1-4):687-98. PubMed PMID: 1653353.
2. Adamantidis MM, Honor? ER, Dupuis BA. Electrical and mechanical effects of new aminosteroids on guinea-pig isolated ventricular muscle. Br J Pharmacol. 1988 Dec;95(4):1063-74. PubMed PMID: 2851356; PubMed Central PMCID: PMC1854287.
3. Brown L. Positive inotropic and vasoconstrictor responses to 14 beta-aminopregnane derivatives in isolated tissues from the guinea-pig. Clin Exp Pharmacol Physiol. 1990 Aug;17(8):589-94. PubMed PMID: 2208801.
4. Maixent JM, Gerbi A, Berrebi-Bertrand I, Correa PE, Genain G, Baggioni A. Cordil reversibly inhibits the Na,K-ATPase from outside of the cell membrane. Role of K-dependent dephosphorylation. J Recept Res. 1993;13(7):1083-92. PubMed PMID: 8396181.