Lysylphosphatidylglycerol

TargetMol
Product Code: TAR-T33094
Supplier: TargetMol
CodeSizePrice
TAR-T33094-5mg5mg£850.00
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Quantity:
TAR-T33094-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T33094-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Lysylphosphatidylglycerol is glycerol with two fatty acids plus a lysine-glycerol-phosphate, a major membrane phospholipid of Staphylococcus and the lysine positive charge repels DEFENSINS.
CAS:
42241-11-2
Formula:
C9H21N2O7P
Molecular Weight:
300.248
Purity:
0.98
SMILES:
NCCCC[C@H](N)C(=O)OP(O)(=O)OCC(O)CO

References

1. Atila M, Katselis G, Chumala P, Luo Y. Characterization of N-Succinylation of L-Lysylphosphatidylglycerol in Bacillus subtilis Using Tandem Mass Spectrometry. J Am Soc Mass Spectrom. 2016 Oct;27(10):1606-13. doi: 10.1007/s13361-016-1455-4. Epub 2016 Aug 9. PubMed PMID: 27506207. 2. Staubitz P, Neumann H, Schneider T, Wiedemann I, Peschel A. MprF-mediated biosynthesis of lysylphosphatidylglycerol, an important determinant in staphylococcal defensin resistance. FEMS Microbiol Lett. 2004 Feb 9;231(1):67-71. PubMed PMID: 14769468. 3. Bandyopadhyay A, McCarthy KA, Kelly MA, Gao J. Targeting bacteria via iminoboronate chemistry of amine-presenting lipids. Nat Commun. 2015 Mar 12;6:6561. doi: 10.1038/ncomms7561. PubMed PMID: 25761996; PubMed Central PMCID: PMC4363082. 4. Gould RM, Dawson RM. The trypsin-catalyzed hydrolysis of monomolecular films of lysylphosphatidylglycerol. Biochim Biophys Acta. 1972 Oct 23;288(1):1-11. PubMed PMID: 4640386.