Majonoside R2
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Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Majonoside R2 is a major saponin constituent of Vietnamese ginseng.
CAS:
81534-63-6
Formula:
C41H70O14
Molecular Weight:
786.997
Purity:
0.98
SMILES:
[H][C@@]12[C@H](CC[C@@]1(C)[C@]1(C)C[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)C3C(C)(C)[C@H](O)CC[C@]3(C)[C@@]1([H])C[C@@H]2O)[C@]1(C)CC[C@H](O1)C(C)(C)O
References
Jeong JJ, Van Le TH, Lee SY, Eun SH, Nguyen MD, Park JH, Kim DH. Anti-inflammatory effects of vina-ginsenoside R2 and majonoside R2 isolated from Panax vietnamensis and their metabolites in lipopolysaccharide-stimulated macrophages. Int Immunopharmacol. 2015 Sep;28(1):700-6. doi: 10.1016/j.intimp.2015.07.025. Epub 2015 Aug 5. PubMed PMID: 26256699.
Huong NT, Matsumoto K, Yamasaki K, Duc NM, Nham NT, Watanabe H. Majonoside-R2, a major constituent of Vietnamese ginseng, attenuates opioid-induced antinociception. Pharmacol Biochem Behav. 1997 May-Jun;57(1-2):285-91. PubMed PMID: 9164584.
Lee SY, Jeong JJ, Le TH, Eun SH, Nguyen MD, Park JH, Kim DH. Ocotillol, a Majonoside R2 Metabolite, Ameliorates 2,4,6-Trinitrobenzenesulfonic Acid-Induced Colitis in Mice by Restoring the Balance of Th17/Treg Cells. J Agric Food Chem. 2015 Aug 12;63(31):7024-31. doi: 10.1021/acs.jafc.5b02183. Epub 2015 Jul 30. PubMed PMID: 26194345.
Nguyen TT, Matsumoto K, Yamasaki K, Watanabe H. Involvement of supraspinal GABA receptors in majonoside-R2 suppression of clonidine-induced antinociception in mice. Life Sci. 1997;61(4):427-36. PubMed PMID: 9244369.