Ochraceolide A
Code | Size | Price |
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TAR-T33772-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Ochraceolide A is isolated from Kokoona ochracea stem bark.
CAS:
138913-61-8
Formula:
C30H44O3
Molecular Weight:
452.679
Purity:
0.98
SMILES:
[H][C@]12[C@H]3C(C[C@]1(C)CC[C@]1(C)[C@]2([H])CC[C@]2([H])[C@@]4(C)CCC(=O)C(C)(C)[C@]4([H])CC[C@@]12C)OC(=O)C3=C
References
Mi Q, Lantvit D, Reyes-Lim E, Chai H, Zhao W, Lee IS, Peraza-S?nchez S, Ngassapa O, Kardono LB, Riswan S, Hollingshead MG, Mayo JG, Farnsworth NR, Cordell GA, Kinghorn AD, Pezzuto JM. Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests. J Nat Prod. 2002 Jun;65(6):842-50. PubMed PMID: 12088425.
Ngassapa OD, Soejarto DD, Che CT, Pezzuto JM, Farnsworth NR. New cytotoxic lupane lactones from Kokoona ochracea. J Nat Prod. 1991 Sep-Oct;54(5):1353-9. PubMed PMID: 1800637.
Sturm S, Gil RR, Chai HB, Ngassapa OD, Santisuk T, Reutrakul V, Howe A, Moss M, Besterman JM, Yang SL, Farthing JE, Tait RM, Lewis JA, O'Neill MJ, Farnsworth NR, Cordell GA, Pezzuto JM, Kinghorn AD. Lupane derivatives from Lophopetalum wallichii with farnesyl protein transferase inhibitory activity. J Nat Prod. 1996 Jul;59(7):658-63. PubMed PMID: 8759161.
Herrera-Espa?a AD, Mena-Rej?n GJ, Hern?ndez-Ortega S, Quijano L, Mir?n-L?pez G. Crystal structure of ochraceolide A isolated from Elaeodendron trichotomum (Turcz.) Lundell. Acta Crystallogr E Crystallogr Commun. 2017 Sep 15;73(Pt 10):1475-1478. doi: 10.1107/S2056989017012816. eCollection 2017 Oct 1. PubMed PMID: 29250361; PubMed Central PMCID: PMC5730298.