Opc 8490
Code | Size | Price |
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TAR-T33807-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T33807-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T33807-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Opc 8490 is a positive inotropic agent.
CAS:
123941-50-4
Formula:
C30H35N3O10
Molecular Weight:
597.621
Purity:
0.98
SMILES:
OC(=O)CC(O)(CC(O)=O)C(O)=O.O=C(CCCN1CCN(CC1)C(=O)c1ccc2NC(=O)CCc2c1)c1ccccc1
References
Furukawa Y, Akahane K, Haniuda M, Chiba S. Positive inotropic and negative chronotropic effects of OPC-8490, a newly developed cardiotonic, in isolated, blood-perfused canine heart preparations. Jpn Heart J. 1989 May;30(3):387-98. PubMed PMID: 2552190.
Endoh M, Satoh H, Norota I, Hirano K, Hosokawa T. Subcellular mechanism of the positive inotropic effect of a new quinolinone derivative OPC-8490 on the dog ventricular myocardium. Heart Vessels. 1991;6(3):158-67. PubMed PMID: 1655692.
Kurachi Y, Asano Y, Ito H, Sugimoto T. Voltage-dependent inhibition of the delayed outward potassium current by OPC-8490, a novel positive inotropic agent, in isolated atrial myocytes of guinea-pig heart. Naunyn Schmiedebergs Arch Pharmacol. 1990 Apr;341(4):324-30. PubMed PMID: 1692107.
Focaccio A, Peeters G, Movsesian M, Roden R, Eki Y, Krall J, Bristow MR. Mechanism of action of OPC-8490 in human ventricular myocardium. Circulation. 1996 Feb 15;93(4):817-25. PubMed PMID: 8641012.