Tibenelast
| Code | Size | Price |
|---|
| TAR-T34874-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Tibenelast is a cioactive chemical.
CAS:
97852-72-7
Formula:
C13H14O4S
Molecular Weight:
266.31
Purity:
0.98
SMILES:
CCOc1cc2cc(sc2cc1OCC)C(O)=O
References
Spina D, Ferlenga P, Biasini I, Moriggi E, Marchini F, Semeraro C, Page CP. The effect duration of selective phosphodiesterase inhibitors in the guinea pig. Life Sci. 1998;62(11):953-65. PubMed PMID: 9515552.
Louis R, Bury T, Corhay JL, Radermecker M. LY 186655, a phosphodiesterase inhibitor, inhibits histamine release from human basophils, lung and skin fragments. Int J Immunopharmacol. 1992 Feb;14(2):191-4. PubMed PMID: 1378045.
Ho PP, Wang LY, Towner RD, Hayes SJ, Pollock D, Bowling N, Wyss V, Panetta JA. Cardiovascular effect and stimulus-dependent inhibition of superoxide generation from human neutrophils by tibenelast, 5,6-diethoxybenzo(b)thiophene-2-carboxylic acid, sodium salt (LY186655). Biochem Pharmacol. 1990 Nov 1;40(9):2085-92. PubMed PMID: 2173601.
Schwertschlag US, Cerimele BJ, McNay JL, Bowsher RR, Rowe H. Effect of tibenelast (a phosphodiesterase inhibitor) and theophylline on isoproterenol-stimulated heart rate, cyclic AMP and norepinephrine levels. Pharmacology. 1993;46(3):142-7. PubMed PMID: 8382824.