UK 1745
| Code | Size | Price |
|---|
| TAR-T34987-5mg | 5mg | £1,167.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
UK 1745 is a novel drug of cardiotonic.
CAS:
170684-14-7
Formula:
C16H23ClN2O2
Molecular Weight:
310.82
Purity:
0.98
SMILES:
Cl.C[C@H]1c2cc(C)c3NC(=O)C(C)(C)c3c2O[C@@]1(C)CN
References
Sawada H, Endoh M. Pharmacological characterization of effects of UK-1745, a novel cardiotonic agent with beta-adrenoceptor-blocking action, in aequorin-loaded canine right ventricular muscle. J Mol Cell Cardiol. 1999 May;31(5):1047-62. PubMed PMID: 10336843.
Uchida Y, Kawada M, Sawanobori K, Sonoki H, Inoue K, Mizuno K, Itou T, Tabunoki Y, Tsukamoto M, Ohashi Y, Kyotani Y, Shimizu N, Fujii M, Nakamura M. Cardiovascular effects of (2RS,3SR)- 2-aminomethyl-2,3,7,8-tetrahydro-2,3,5,8,8-pentamethyl-6H-furo- [2,3-e]indol-7-one hydrochloride (UK-1745), a novel cardiotonic agent with vasodilatory and antiarrhythmic properties. Arzneimittelforschung. 1998 Mar;48(3):219-31. PubMed PMID: 9553677.
Uemura H, Sakamoto N, Nakaya H. Electropharmacological effects of UK-1745, a novel cardiotonic drug, in guinea-pig ventricular myocytes. Eur J Pharmacol. 1999 Nov 3;383(3):361-71. PubMed PMID: 10594330.