Licochalcone A
| Code | Size | Price |
|---|
| TAR-T3600-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3600-20mg | 20mg | £151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Licochalcone A is a flavonoid isolated from the famous Chinese medicinal herb Glycyrrhiza uralensis Fisch with obvious anti-cancer effects.
CAS:
58749-22-7
Formula:
C21H22O4
Molecular Weight:
338.403
Pathway:
Autophagy; Apoptosis; Metabolism; Proteases/Proteasome
Purity:
0.9811
SMILES:
COc1cc(O)c(cc1C=CC(=O)c1ccc(O)cc1)C(C)(C)C=C
Target:
Caspase; UGT; Autophagy
References
Egler J, et al. Licochalcone A Induced Suicidal Death of Human Erythrocytes. Cell Physiol Biochem. 2015;37(5):2060-70.
Hao W, et al. Sci Rep. 2015, 5, 10336.
Hong Xin, et al. Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. Food and Chemical Toxicology Volume 90, April 2016, Pages 112?122
Lee CK, et al. Basic Clin Pharmacol Toxicol. 2008, 103(1), 48-54.
Chen M, et al. Antimicrob Agents Chemother. 1993, 37(12), 2550-2556.
Tsukiyama R, et al. Antimicrob Agents Chemother. 2002, 46(5), 1226-1230.
Tang ZH, et al. Induction of C/EBP homologous protein-mediated apoptosis and autophagy by licochalcone A in non-small cell lung cancer cells. Sci Rep. 2016 May 17;6:26241.
Chen M, et al. Antimicrob Agents Chemother. 1994, 38(6), 1339-1344.