Eleutheroside E
| Code | Size | Price |
|---|
| TAR-T3662-1mL | 1 mL * 10 mM (in DMSO) | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3662-20mg | 20mg | £151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Eleutheroside E has anti-inflammatory effects by inhibiting NF-κB activities. Eleutheroside E significantly decreases the inflammatory cell infiltration, pannus formation, cartilage damage, bone erosion of CIA mice, the generation of TNF-α and IL-6, the metabolism of drugs metabolized via CYP2C9 and CYP2E1. Eleutheroside E may treat rheumatoid arthritis or increase the toxicity of the drugs.
CAS:
39432-56-9
Formula:
C34H46O18
Molecular Weight:
742.724
Pathway:
NF-κb
Purity:
0.9943
SMILES:
COc1cc(cc(OC)c1O[C@H]1O[C@@H](CO)[C@H](O)[C@@H](O)[C@@H]1O)[C@H]1OC[C@H]2[C@@H]1CO[C@H]2c1cc(OC)c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c(OC)c1
Target:
NF-κB
References
Kil YS, et al. Arch Pharm Res. 2015 Nov;38(11):1921-5.
He C, et al. Inflammation. 2014 Oct;37(5):1533-43.
Jung M A, Song H K, Jo K, et al.Gleditsia sinensis Lam. aqueous extract attenuates nasal inflammation in allergic rhinitis by inhibiting MUC5AC production through suppression of the STAT3/STAT6 pathway.Biomedicine & Pharmacotherapy.2023, 161: 114482.