(R)-Omeprazole (sodium salt)
Code | Size | Price |
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TAR-T36840-5mg | 5mg | £879.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
(R)-Omeprazole is the inactive isomer of omeprazole , a gastric proton-pump inhibitor. A stereoselective hydroxylation of (R)-omeprazole is mediated primarily by cytochrome P450 (CYP) 2C19, whereas CYP3A4 favors sulfoxidation of the active (S)-enantiomer . (R)-Omeprazole has been shown to act as a reversible direct-acting and metabolism-dependent inhibitor of CYP2C19 in pooled human liver microsomes (IC50 = 8.1 μM).
CAS:
161796-77-6
Formula:
C17H20N3NaO3S
Molecular Weight:
369.41
Purity:
0.98
SMILES:
[NaH].COc1ccc2nc([nH]c2c1)S(=O)Cc1ncc(C)c(OC)c1C