Epifriedelanol
| Code | Size | Price |
|---|
| TAR-T3768-5mg | 5mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Epifriedelanol suppresses adriamycin-induced cellular senescence, replicative senescence in human fibroblasts (HDFs) and HUVECs. Because of Epifriedelanol can reduce cellular senescence in human primary cells, it may be used to develop dietary supplements or cosmetics that modulate tissue aging or aging-associated diseases.
CAS:
16844-71-6
Formula:
C31H54O
Molecular Weight:
442.772
Purity:
0.9975
SMILES:
C[C@H]1[C@@H](O)CC[C@H]2[C@]1(C)CC[C@@]1(C)[C@@]2(C)CC[C@@]2(C)[C@@H]3CC(C)(C)CC[C@]3(C)CC[C@]12C
References
Yang HH., et al. Epifriedelanol from the root bark of Ulmus davidiana inhibits cellular senescence in human primary cells.Planta Med. 2011 Mar;77(5):441-9.
Cai J., et al. Potent protein tyrosine phosphatase 1B (PTP1B) inhibiting constituents from Anoectochilus chapaensis and molecular docking studies. Pharm Biol. 2015 Jul;53(7):1030-4.
Kundu JK., et al. Antitumor activity of epifriedelanol from Vitis trifolia. Fitoterapia. 2000 Sep;71(5):577-9.
Jia LY., et al. A new cycloartane nortriterpenoid from stem and leaf of Quercus variabilis. J Asian Nat Prod Res. 2013 Sep;15(9):1050-4.
Wang, Y. et al.: Spectrochim Acta A Mol Biomol. Spectrosc., 153, 645 (2016)