Tenuigenin
| Code | Size | Price |
|---|
| TAR-T3907-1mL | 1 mL * 10 mM (in DMSO) | £135.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T3907-20mg | 20mg | £151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.
CAS:
2469-34-3
Formula:
C30H45ClO6
Molecular Weight:
537.13
Pathway:
NF-κb; Proteases/Proteasome; Apoptosis; Microbiology/Virology
Purity:
0.989
SMILES:
CC1(C)CC[C@@]2(CCC3=C([C@@H](CCl)C[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)[C@](C)([C@@H]5CC[C@@]34C)C(O)=O)[C@@H]2C1)C(O)=O
Target:
NF-κB; Caspase; Antibacterial
References
Xie W, Yang Y, Gu X, Zheng Y,et al.Senegenin attenuates hepatic ischemia-reperfusion induced cognitive dysfunction by increasing hippocampal NR2B expression in rats.PLoS One. 2012;7(9):e45575.
Li X, Zhao Y, Liu P,et al.Senegenin Inhibits Hypoxia/Reoxygenation-Induced Neuronal Apoptosis by Upregulating RhoGDI?.Mol Neurobiol. 2015 Dec;52(3):1561-71.
Yu L , Sun L , Chen S .Protective effect of senegenin on splenectomy-induced postoperative cognitive dysfunction in elderly rats.Exp Ther Med. 2014 Apr;7(4):821-826.