MS33
Code | Size | Price |
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TAR-T39975-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
MS33 is a potent WDR5 degrader, with K d s of 870 nM and 120 nM for VCB and WDR5 , respectively. MS33 induces WDR5 degradation in an E3 ligase VHL, and proteasome-dependent manner. MS33 can be used for the research of acute myeloid leukemia.
CAS:
2407449-11-8
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Yu X, et, al. A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models. Sci Transl Med. 2021 Sep 29;13(613):eabj1578.