AS8351

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TargetMol
Product Code: TAR-T4100
Supplier: TargetMol
CodeSizePrice
TAR-T4100-5mg5mg£105.00
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TAR-T4100-1mL1 mL * 10 mM (in DMSO)£108.00
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Quantity:
TAR-T4100-10mg10mg£122.00
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Quantity:
TAR-T4100-25mg25mg£165.00
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Quantity:
TAR-T4100-50mg50mg£230.00
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Quantity:
TAR-T4100-100mg100mg£367.00
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Quantity:
TAR-T4100-200mg200mg£455.00
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TAR-T4100-500mg500mg£701.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AS-8351 is a histone demethylase inhibitor. It has been used in combination with CHIR99021, A 83-01, BIX01294, SC-1, Y-27632, OAC2, SU 16f, and JNJ-10198409 to induce reprogramming of human fetal lung fibroblasts into functional cardiomyocytes.
CAS:
796-42-9
Formula:
C17H13N3O2
Molecular Weight:
291.31
Pathway:
Chromatin/Epigenetic
Purity:
0.998
SMILES:
NN(C=C1/C(=O)C=Cc2ccccc12)C(=O)c1ccncc1
Target:
Histone Demethylase

References

Cao, N.,Huang, et al.?Conversion of human fibroblasts into functional cardiomyocytes by small molecules.?Science?352(6290),?1216-1220?(2016). Chen B, Chen H, Lu S, et al. KDM5B promotes tumorigenesis of Ewing sarcoma via FBXW7/CCNE1 axis. Cell Death & Disease. 2022, 13(4): 1-13