Daphnoretin
| Code | Size | Price |
|---|
| TAR-T4S1335-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4S1335-20mg | 20mg | £151.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
1. Daphnoretin has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through promoting apoptosis in a mitochondria-mediated way. 3. Daphnoretin causes death of HOS cells by blocking cells successively in G2/M phases and activating the caspase-3 pathway.
CAS:
2034-69-7
Formula:
C19H12O7
Molecular Weight:
352.298
Pathway:
Chromatin/Epigenetic; Microbiology/Virology; Apoptosis; Proteases/Proteasome; Cytoskeletal Signaling
Purity:
0.998
SMILES:
COc1cc2cc(Oc3ccc4ccc(=O)oc4c3)c(=O)oc2cc1O
Target:
Influenza Virus; Caspase; PKC
References
Jiang H , Wu Z , Bai X , et al. Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro[J]. Oncology Letters, 2014, 8(3):1139---1142.