Ginsenoside Rk1
| Code | Size | Price |
|---|
| TAR-T4S1499-5mg | 5mg | £146.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures. Ginsenoside Rk1 has an anti-inflammatory effect, suppresses the activation of Jak2/Stat3 signaling pathway and NF-κB. It also has an anti-tumor effect.
CAS:
494753-69-4
Formula:
C42H70O12
Molecular Weight:
767.01
Pathway:
NF-κb; Chromatin/Epigenetic; JAK/STAT signaling; ; Stem Cells; Apoptosis; PI3K/Akt/mTOR signaling; Angiogenesis
Purity:
0.9913
SMILES:
[H][C@@]12[C@H](CC[C@@]1(C)[C@]1(C)CC[C@@]3([H])C(C)(C)[C@H](CC[C@]3(C)[C@@]1([H])C[C@H]2O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C(=C)CCC=C(C)C
Target:
Apoptosis; NF-κB; PI3K; JAK
References
Yu Q, et al. Ginsenoside Rk1 suppresses pro-inflammatory responses in lipopolysaccharide-stimulated RAW264.7 cells by inhibiting the Jak2/Stat3 pathway. Chin J Nat Med. 2017 Oct;15(10):751-757.
Kim JS, et al. Induction of apoptosis by ginsenoside Rk1 in SK-MEL-2-human melanoma. Arch Pharm Res. 2012 Mar;35(4):717-22.