N-(3-Phenylpropionyl)glycine

TargetMol
Product Code: TAR-T5215
Supplier: TargetMol
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TAR-T5215-50mg50mgEnquire
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TAR-T5215-1mL1 mL * 10 mM (in DMSO)£94.00
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TAR-T5215-10mg10mg£97.00
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TAR-T5215-25mg25mg£111.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
N-(3-Phenylpropionyl)glycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. Acyl glycines are produced through the action of glycine N-acyltransferase which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycineThe detection of phenylpropionylglycine in urine after an oral load of phenylpropionic acid can be used to diagnose deficiency of medium-chain acyl-CoA dehydrogenase, a frequent and treatable metabolic defect.
CAS:
56613-60-6
Formula:
C11H13NO3
Molecular Weight:
207.229
Purity:
0.9725
SMILES:
OC(=O)CNCCC(=O)c1ccccc1

References

Flath B, et al. Simple high-performance liquid chromatographic method for the detection of phenylpropionylglycine in urine as a diagnostic tool in inherited medium-chain acyl-coenzyme A dehydrogenase deficiency. J Chromatogr B Biomed Sci Appl. 1997 Jun 20;694(1):227-32.