YKL-06-061

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TargetMol
Product Code: TAR-T5576
Supplier: TargetMol
CodeSizePrice
TAR-T5576-1mg1mg£95.00
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TAR-T5576-5mg5mg£127.00
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TAR-T5576-1mL1 mL * 10 mM (in DMSO)£136.00
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TAR-T5576-10mg10mg£171.00
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TAR-T5576-25mg25mg£258.00
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TAR-T5576-50mg50mg£389.00
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TAR-T5576-100mg100mg£563.00
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TAR-T5576-500mg500mg£1,131.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.
CAS:
2172617-15-9
Formula:
C30H37N7O2
Molecular Weight:
527.673
Pathway:
PI3K/Akt/mTOR signaling; Chromatin/Epigenetic
Purity:
0.9981
SMILES:
COc1cc(ccc1Nc1ncc2CN(C(=O)N(C3CCC3)c2n1)c1c(C)cccc1C)N1CCN(C)CC1
Target:
AMPK; SIK

References

Mujahid N, et al. A UV-Independent Topical Small-Molecule Approach for Melanin Production in Human Skin. Cell Rep. 2017 Jun 13;19(11):2177-2184.