10-Deacetyl-7-xylosyl paclitaxel

TargetMol
Product Code: TAR-T5749
Supplier: TargetMol
CodeSizePrice
TAR-T5749-5mg5mg£111.00
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Quantity:
TAR-T5749-1mL1 mL * 10 mM (in DMSO)£147.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
7-Xylosyl-10-deacetyltaxol paclitaxel is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.
CAS:
90332-63-1
Formula:
C50H57NO17
Molecular Weight:
943.996
Pathway:
; Cytoskeletal Signaling
Purity:
0.9976
SMILES:
[H][C@@]12C[C@H](O[C@@H]3OC[C@@H](O)[C@H](O)[C@H]3O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@H](C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C)OC(=O)[C@H](O)[C@@H](NC(=O)c1ccccc1)c1ccccc1
Target:
Microtubule Associated

References

Jiang S , Zu Y , Zhang Y , et al. Transport of a Hydrophilic Paclitaxel Derivative, 7-Xylosyl-10-Deacetylpaclitaxel, by Human Intestinal Epithelial Caco-2 Cells[J]. Planta medica, 2010, 76(14). Jiang S , Zu Y , Fu Y , et al. Activation of the mitochondria-driven pathway of apoptosis in human PC-3 prostate cancer cells by a novel hydrophilic paclitaxel derivative, 7-xylosyl-10-deacetylpaclitaxel[J]. International Journal of Oncology, 2008, 33(1):103---111.