Indirubin

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TargetMol
Product Code: TAR-T6169
Supplier: TargetMol
CodeSizePrice
TAR-T6169-5mg5mg£107.00
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Quantity:
TAR-T6169-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T6169-10mg10mg£119.00
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Quantity:
TAR-T6169-25mg25mg£152.00
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Quantity:
TAR-T6169-50mg50mg£204.00
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Quantity:
TAR-T6169-100mg100mg£302.00
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Quantity:
TAR-T6169-200mg200mg£371.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Indirubin is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 of about 5 uM and 0.6 uM.
CAS:
479-41-4
Formula:
C16H10N2O2
Molecular Weight:
262.268
Pathway:
MAPK; Apoptosis; PI3K/Akt/mTOR signaling; Cell Cycle/Checkpoint; Stem Cells
Purity:
0.9786
SMILES:
O=C1Nc2ccccc2C1=C1/Nc2ccccc2C1=O
Target:
Apoptosis; Raf; GSK-3; CDK

References

Sethi G, et al. J Biol Chem, 2006, 281(33), 23425-2335. Leclerc S, et al. J Biol Chem, 2001, 276(1), 251-260. Hoessel R, et al. Nat Cell Biol, 1999, 1(1), 60-67.