7-Methylguanosine
| Code | Size | Price |
|---|
| TAR-T7319-5mg | 5mg | £95.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T7319-50mg | 50mg | £139.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
7-Methylguanosine is a novel cNIIIB nucleotidase inhibitor (IC50 : 87.8 ? 7.5 μM).
CAS:
20244-86-4
Formula:
C11H16N5O5
Molecular Weight:
298.278
Pathway:
DNA Damage/DNA Repair; Metabolism; Cell Cycle/Checkpoint
Purity:
1
SMILES:
C[n+]1cn([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)c2nc(N)[nH]c(=O)c12
Target:
Nucleoside Antimetabolite/Analog; Endogenous Metabolite
References
Kozarski M, Kubacka D, Wojtczak BA,et al.7-Methylguanosine Modifications in Transfer RNA (tRNA).Bioorg Med Chem. 2018 Jan 1;26(1):191-199.
Kozarski M , Kubacka D , Wojtczak B A , et al. 7-Methylguanosine monophosphate analogues with 5'-(1,2,3-triazoyl) moiety: Synthesis and evaluation as the inhibitors of cNIIIB nucleotidase[J]. Bioorganic & Medicinal Chemistry, 2018, 26(1):191.