Alloxan monohydrate
| Code | Size | Price |
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| TAR-T7814-1g | 1g | £94.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.
CAS:
2244-11-3
Formula:
C4H4N2O5
Molecular Weight:
160.085
Pathway:
Ubiquitination; Proteases/Proteasome
Purity:
0.98
SMILES:
O.O=C1NC(=O)C(=O)C(=O)N1
Target:
Proteasome
References
Szkuldeshi T . The mechanism of alloxan and streptozotocin action in beta cells of the rat pancreas[J]. Physiol Rev. 2001, 50.
Zhou W , Wei L , Xiao T , et al. Diabetogenic agent alloxan is a proteasome inhibitor.[J]. Biochemical & Biophysical Research Communications, 2017, 488(2).
Major species differences between humans and rodents in the susceptibility to pancreatic ?-cell injury.