Canthin-6-one

TargetMol
Product Code: TAR-TN1466
Supplier: TargetMol
CodeSizePrice
TAR-TN1466-5mg5mg£417.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-TN1466-1mL1 mL * 10 mM (in DMSO)£808.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; it also has antiinflammatory activity by interfering with the transcription factors NF-κB and AP-1 at transcriptional level.
CAS:
479-43-6
Formula:
C14H8N2O
Molecular Weight:
220.231
Pathway:
Proteases/Proteasome; Apoptosis; Microbiology/Virology; NF-κb
Purity:
0.98
SMILES:
O=c1ccc2nccc3c4ccccc4n1c23
Target:
NF-κB; Caspase; Antifection

References

Canthin-6-one alkaloids from Picrasma quassioides and their cytotoxic activity.J Asian Nat Prod Res. 2008 Nov-Dec;10(11-12):1009-12.