4,5-Dimethoxycanthin-6-one
Code | Size | Price |
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TAR-TN3013-1mg | 1mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN3013-1mL | 1 mL * 10 mM (in DMSO) | £341.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN3013-5mg | 5mg | £369.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN3013-10mg | 10mg | £550.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN3013-25mg | 25mg | £821.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TN3013-50mg | 50mg | £1,083.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
4,5-Dimethoxycanthin-6-one has antibacterial actiyity, it exhibits inhibition against Staphylococcus aureus and its drug-resistant strains. 4,5-Dimethoxycanthin-6-one has a strong inhibitory effect on cyclic adenosine monophosphate (cAMP) phosphodiesterase. It also shows cytotoxicity against the tumor cell lines, U937 and HepG2.
CAS:
18110-87-7
Formula:
C16H12N2O3
Molecular Weight:
280.3
Pathway:
GPCR/G Protein; Microbiology/Virology
Purity:
0.98
SMILES:
COc1c(OC)c(=O)n2c3ccccc3c3ccnc1c23
Target:
cAMP; Antifection
References
Miao X, et al. In vitro metabolism of 4, 5-dimethoxycanthin-6-one by human liver microsomes and its inhibition on human CYP1ALife Sci. 2017;190:46-51.
Li W, et al. 4,5-Dimethoxycanthin-6-one is a novel LSD1 inhibitor that inhibits proliferation of glioblastoma cells and induces apoptosis and pyroptosis. Cancer Cell Int. 2022;22(1):32.
OHMoTo T, et al. Studies on the constituents of Picrasma quassioides BENNET. III. The alkaloidal constituents. Chemical and pharmaceutical bulletin. 1984;32(9): 3579-3583.