(+)-Lyoniresinol
| Code | Size | Price |
|---|
| TAR-TN4469-5mg | 5mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lyoniresinol has antioxidant effect, it shows robust anti-melanogenic activity, decreases tyrosinase activity and melanin biosynthesis in B16F10 cells by activating ERK signaling, which downregulated MITF, tyrosinase, but not TRP-1 and TRP-2 protein expression.
CAS:
14464-90-5
Formula:
C22H28O8
Molecular Weight:
420.5
Pathway:
Membrane transporter/Ion channel; MAPK
Purity:
0.98
SMILES:
COc1cc(cc(OC)c1O)[C@@H]1[C@@H](CO)[C@H](CO)Cc2cc(OC)c(O)c(OC)c12
Target:
ERK; TRP/TRPV Channel
References
Liu H, et al. Lyoniresinol inhibits melanogenic activity through the induction of microphthalmia-associated transcription factor and extracellular receptor kinase activation. Mol Cell Biochem. 2013;373(1-2):211-216.
Yang XW, et al. Tarennanosides A-H, eight new lignan glucosides from Tarenna attenuata and their protective effect on H2O2-induced impairment in PC12 cells. Chem Biodivers. 2009;6(4):540-550.