Grasshopper ketone
| Code | Size | Price |
|---|
| TAR-TN5387-5mg | 5mg | £1,434.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-TN5387-1mL | 1 mL * 10 mM (in DMSO) | £1,707.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Grasshopper ketone, isolated from the brown alga Sargassum, is a potent inhibitor of LPS-induced NO production in RAW 264.7 cells and induces anti-inflammatory effects by inhibiting MAPK (ERK, JNK and p38) and NF-κB p65 phosphorylation.
CAS:
41703-38-2
Formula:
C13H20O3
Molecular Weight:
0
Pathway:
MAPK|Immunology/Inflammation
Purity:
0.98
SMILES:
CC(=O)C=C=C1C(C)(C)CC(O)C[C@@]1(C)O
Target:
NO Synthase|p38 MAPK|ERK|JNK
References
Kim MJ, et al. Anti-Inflammatory Effects of Grasshopper Ketone from Sargassum fulvellum Ethanol Extract on Lipopolysaccharide-Induced Inflammatory Responses in RAW 264.7 Cells. J Microbiol Biotechnol. 2019 ; 29(5):820-826.
Kang BK, et al. In vivo and in vitro inhibitory activity of an ethanolic extract of Sargassum fulvellum and its component grasshopper ketone on atopic dermatitis. Int Immunopharmacol. 2016 ; 40:176-183.
Kato-Noguchi H, et al. Identification of two phytotoxins, blumenol A and grasshopper ketone, in the allelopathic Japanese rice variety Awaakamai. J Plant Physiol. 2012 ; 169(7):682-685.