Epothilone D
Code | Size | Price |
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TAR-TQ0202-5mg | 5mg | £201.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0202-1mL | 1 mL * 10 mM (in DMSO) | £211.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-TQ0202-25mg | 25mg | £491.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Epothilone D (KOS 862) is an effective microtubule stabilizer.
CAS:
189453-10-9
Formula:
C27H41NO5S
Molecular Weight:
491.69
Pathway:
Cytoskeletal Signaling
Purity:
0.98
SMILES:
CC1CCCC(C)=CCC(OC(=O)CC(O)C(C)(C)C(=O)C(C)C1O)C(C)=Cc1csc(C)n1
Target:
Microtubule Associated
References
Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy. J Neurosci. 2010 Oct 13;30(41):13861-6.
Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma. Invest New Drugs. 2012 Dec;30(6):2294-302.