4-O-Methyl honokiol
Code | Size | Price |
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TAR-T10153-1mL | 1 mL * 10 mM (in DMSO) | £181.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T10153-10mg | 10mg | £229.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
4-O-Methyl honokiol, a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist and inhibits NF-κB activity, used for cancer and inflammation research.
CAS:
68592-15-4
Formula:
C19H20O2
Molecular Weight:
280.367
Purity:
0.98
SMILES:
COc1ccc(cc1CC=C)-c1cc(CC=C)ccc1O
References
1. Lee NJ, et al. 4-O-methylhonokiol, a PPAR? agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-?B activity. Br J Pharmacol. 2013 Mar;168(5):1133-45.
2. Lee YJ, et al. Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models. J Neuroinflammation. 2012 Feb 19;9:35.