(±)-10-Hydroxycamptothecin
Code | Size | Price |
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TAR-T1521-25mg | 25mg | £116.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T1521-50mg | 50mg | £136.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
(?)-10-Hydroxycamptothecin is an alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA topoisomerase, type I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
CAS:
64439-81-2
Formula:
C20H16N2O5
Molecular Weight:
364.35
Pathway:
DNA Damage/DNA Repair
Purity:
0.9958
SMILES:
CCC1(c2c(COC1=O)c(=O)n1Cc3c(c1c2)nc1ccc(cc1c3)O)O
Target:
Topoisomerase
References
1. Zhang S, et al. AntiY Drugs. 2014 Jul;25(6):614-23.