Edoxaban M4
Code | Size | Price |
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TAR-T19873-10mg | 10mg | £524.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T19873-25mg | 25mg | £870.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T19873-50mg | 50mg | £1,324.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
D21-2393 subjects received a single-oral-dose of edoxaban 30-90 mg in each study occasion under fasting condition. Serial blood samples were collected to measure the plasma concentrations of edoxaban and its major active metabolite D21-2393. Meanwhile, PT, INR, aPTT were measured pre- and post-dose.
CAS:
834919-19-6
Formula:
C22H25ClN6O5S
Molecular Weight:
520.99
Purity:
0.98
SMILES:
CN1CCc2nc(sc2C1)C(=O)N[C@@H]1C[C@H](CC[C@@H]1NC(=O)C(=O)Nc1ccc(Cl)cn1)C(O)=O
References
1. Chen X, Liu D, Wu Y, Song H, Liu Y, Jiang J, Hu P. A single-dose study investigating the pharmacokinetics and pharmacodynamics of edoxaban at 30-90?mg in healthy Chinese volunteers. Xenobiotica. 2017 Jul;47(7):592-599. doi: 10.1080/00498254.2016.1207825. Epub 2016 Aug 25. PubMed PMID: 27560456.
2. Chen X, Liu D, Wu Y, Liu Y, Song H, Jiang J, Hu P. A single and multiple postprandial dose study investigating the pharmacokinetics and pharmacodynamics of edoxaban in healthy Chinese volunteers?. Int J Clin Pharmacol Ther. 2017 Mar;55(3):256-263. doi: 10.5414/CP202737. PubMed PMID: 28025966.