NG,NG-dimethyl-L-Arginine dihydrochloride
Code | Size | Price |
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TAR-T21546-10mg | 10mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21546-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21546-5mg | 5mg | £105.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T21546-1mL | 1 mL * 10 mM (in DMSO) | £113.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
NG,NG-dimethyl-L-Arginine dihydrochloride is an endogenous nitric oxide synthase inhibitor. Nitric oxide (NO) that is synthesised from L-arginine contributes to the regulation of blood pressure and to host defence[1].
CAS:
220805-22-1
Formula:
C8H20Cl2N4O2
Molecular Weight:
275.18
Pathway:
Immunology/Inflammation
Purity:
0.9918
SMILES:
N[C@@H](CCCNC(N(C)C)=N)C(O)=O.[H]Cl.[H]Cl
Target:
NO Synthase
References
1. Wu M, et al. Renal asymmetric dimethylarginine inhibits fibrosis. FEBS Open Bio. 2020 Oct;10(10):2003-2009. doi: 10.1002/2211-5463.12949. Epub 2020 Aug 30.
2. Wu M, et al. Reduced asymmetric dimethylarginine accumulation through inhibition of the type I protein arginine methyltransferases promotes renal fibrosis in obstructed kidneys. FASEB J. 2019 Jun;33(6):6948-6956.