S116836
Code | Size | Price |
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TAR-T24751-5mg | 5mg | £404.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24751-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T24751-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
S116836 is a tyrosine kinase inhibitor.
CAS:
1257628-57-1
Formula:
C27H21F3N6O
Molecular Weight:
502.501
Purity:
0.98
SMILES:
Cc1ccc(cc1C#Cc1cnc(NC2CC2)nc1)C(=O)Nc1cc(cc(c1)C(F)(F)F)-n1ccnc1
References
1. Shen Y, Ren X, Ding K, Zhang Z, Wang D, Pan J. Antitumor activity of S116836, a novel tyrosine kinase inhibitor, against imatinib-resistant FIP1L1-PDGFR?-expressing cells. Oncotarget. 2014 Nov 15;5(21):10407-20. PubMed PMID: 25431951; PubMed Central PMCID: PMC4279382.
2. Bu Q, Cui L, Li J, Du X, Zou W, Ding K, Pan J. SAHA and S116836, a novel tyrosine kinase inhibitor, synergistically induce apoptosis in imatinib-resistant chronic myelogenous leukemia cells. Cancer Biol Ther. 2014 Jul;15(7):951-62. doi: 10.4161/cbt.28931. Epub 2014 Apr 23. PubMed PMID: 24759597; PubMed Central PMCID: PMC4100996.