K 41
| Code | Size | Price |
|---|
| TAR-T25563-10mg | 10mg | £1,033.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
K 41 is a polycyclic polyether antibiotic from Streptomyces hygroscopicus.
CAS:
53026-37-2
Formula:
C48H82O18
Molecular Weight:
947.166
Purity:
0.98
SMILES:
COC1C(C)[C@@]2(O[C@@]1(C)C1CCC(O1)C1CCC(O1)C1OC(C)(O)C(C)C(OC3CCC(OC)C(C)O3)C1C)O[C@H](C[C@H]1O[C@@](O)(C(O)C(O)=O)[C@H](C)[C@@H](OC)[C@]1(C)OC)C[C@@H](OC)[C@H]2C
References
1. Hoshi M, Shimotohno KW, Endo T, Furihata K, Seto H. Microbial and chemical conversion of antibiotic K-41. I. Isolation and identification of conversion product. J Antibiot (Tokyo). 1997 Jul;50(7):631-4. PubMed PMID: 9711256.
2. Otoguro K, Ishiyama A, Ui H, Kobayashi M, Manabe C, Yan G, Takahashi Y, Tanaka H, Yamada H, Omura S. In vitro and in vivo antimalarial activities of the monoglycoside polyether antibiotic, K-41 against drug resistant strains of Plasmodia. J Antibiot (Tokyo). 2002 Sep;55(9):832-4. PubMed PMID: 12458776.
3. Dirlam JP, Bordner J, Cullen WP, Jefferson MT, Presseau-Linabury L. The structure of CP-96,797, a polyether antibiotic related to K-41A and produced by Streptomyces sp. J Antibiot (Tokyo). 1992 Jul;45(7):1187-9. PubMed PMID: 1517165.
4. Hoshi M, Endo T. Microbial and chemical conversion of antibiotic K41. II. Preparation of K41-DA1, -DA2 and -DA3 deamicetosyl derivatives of antibiotic K41. J Antibiot (Tokyo). 2000 Oct;53(10):1154-7. PubMed PMID: 11132961.