Dizocilpine Maleate
Code | Size | Price |
---|
TAR-T3320-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3320-10mg | 10mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3320-25mg | 25mg | £136.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3320-50mg | 50mg | £189.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3320-100mg | 100mg | £286.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T3320-200mg | 200mg | £437.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
(+)-MK-801 is a potent noncompetitive antagonist of the NMDA receptor (RECEPTORS, N-METHYL-D-ASPARTATE) with Kd of 37.2 nM in rat brain membranes. The drug has been considered for the wide variety of neurodegenerative conditions or disorders in which NMDA receptors may play an important role.
CAS:
77086-22-7
Formula:
C20H19NO4
Molecular Weight:
337.38
Pathway:
Membrane transporter/Ion channel; Neuroscience
Purity:
0.9996
SMILES:
c12c([C@]3(c4c([C@@H](C1)N3)cccc4)C)cccc2.C(=O)(/C=CC(=O)O)O
Target:
NMDAR; iGluR
References
Huettner JE, et al. Proc Natl Acad Sci U S A, 1988, 85(4), 1307-1311.
Jiang L, et al. Decrease of growth and differentiation factor 10 contributes to neuropathic pain through N-methyl-D-aspartate receptor activation. Neuroreport. 2017 May 24;28(8):444-450.
Wong EH, et al. Proc Natl Acad Sci U S A, 1986, 83(18), 7104-7108.
Thomas DM, et al. Brain Res, 2005, 1050(1-2), 190-198.
Snell LD, et al. Eur J Pharmacol, 1988, 145(2), 223-226.
Brown TE, et al. Learn Mem, 2008, 15(12), 857-865.